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Inflammasome Activation by Altered Proteostasis
The association between altered proteostasis and inflammatory disorders has been increasingly recognized, but the underlying mechanisms are not well understood. In this study, we show that deficiency of either autophagy or sequestosome 1 (p62 or SQSTM) led to inflammasome hyperactivation in response...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3861638/ https://ncbi.nlm.nih.gov/pubmed/24178293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.514919 |
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