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Cross-sectional and longitudinal changes in DNA methylation with age: an epigenome-wide analysis revealing over 60 novel age-associated CpG sites
Understanding the role of epigenetic modifications, e.g. DNA methylation, in the process of aging requires the characterization of methylation patterns in large cohorts. We analysed >480 000 CpG sites using Infinium HumanMethylation450 BeadChip (Illumina) in whole blood DNA of 965 participants of...
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Hauptverfasser: | , , , , |
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Format: | Artigo |
Sprache: | Inglês |
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Oxford University Press
2014
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3919014/ https://ncbi.nlm.nih.gov/pubmed/24163245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt531 |
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