Broad Antigenic Coverage Induced by Viral cDNA Library-based Vaccination Cures Established Tumors

We show here that a cDNA library of normal tissue, expressed from a highly immunogenic viral platform, cures established tumors of the same histological type from which the cDNA library was derived. With suboptimal vaccination, immune escape was possible, but only when tumor cells were forced to acq...

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Detalhes bibliográficos
Main Authors: Kottke, Timothy, Errington, Fiona, Pulido, Jose, Galivo, Feorillo, Thompson, Jill, Wongthida, Phonphimon, Diaz, Rosa Maria, Chong, Heung, ILett, Elizabeth, Chester, John, Pandha, Hardev, Harrington, Kevin, Selby, Peter, Melcher, Alan, Vile, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918897/
https://ncbi.nlm.nih.gov/pubmed/21685898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2390
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