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Generation and genetic stability of tick-borne encephalitis virus mutants dependent on processing by the foot-and-mouth disease virus 3C protease

Mature protein C of tick-borne encephalitis virus (TBEV) is cleaved from the polyprotein precursor by the viral NS2B/3 protease (NS2B/3(pro)). We showed previously that replacement of the NS2B/3(pro) cleavage site at the C terminus of protein C by the foot-and-mouth disease virus (FMDV) 2A StopGo se...

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Detalhes bibliográficos
Main Authors: Schrauf, Sabrina, Kurz, Martina, Taucher, Christian, Mandl, Christian W., Skern, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918513/
https://ncbi.nlm.nih.gov/pubmed/22131310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.038398-0
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