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An Unusual Topological Structure of the HIV-1 Rev Response Element

Nuclear export of unspliced and singly spliced viral mRNA is a critical step in the HIV life cycle. The structural basis by which the virus selects its own mRNA among more abundant host cellular RNAs for export has been a mystery for more than 25 years. Here, we describe an unusual topological struc...

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Detalhes bibliográficos
Main Authors: Fang, Xianyang, Wang, Jinbu, O’Carroll, Ina P., Mitchell, Michelle, Zuo, Xiaobing, Wang, Yi, Yu, Ping, Liu, Yu, Rausch, Jason W., Dyba, Marzena A., Kjems, Jørgen, Schwieters, Charles D., Seifert, Soenke, Winans, Randall E., Watts, Norman R., Stahl, Stephen J., Wingfield, Paul T., Byrd, R. Andrew, Le Grice, Stuart F.J., Rein, Alan, Wang, Yun-Xing
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918456/
https://ncbi.nlm.nih.gov/pubmed/24243017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.10.008
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