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Siah2 regulates tight junction integrity and cell polarity through control of ASPP2 stability
Changes in cell adhesion and polarity are closely associated with epithelial cell transformation and metastatic capacity. The tumor suppressor protein ASPP2 has been implicated in control of cell adhesion and polarity, through its effect on the PAR complex. Here we demonstrate that under hypoxic con...
Bewaard in:
| Hoofdauteurs: | , , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2013
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3917971/ https://ncbi.nlm.nih.gov/pubmed/23644657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.149 |
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