Ectopic Cerebellar Cell Migration Causes Maldevelopment of Purkinje Cells and Abnormal Motor Behaviour in Cxcr4 Null Mice

SDF-1/CXCR4 signalling plays an important role in neuronal cell migration and brain development. However, the impact of CXCR4 deficiency in the postnatal mouse brain is still poorly understood. Here, we demonstrate the importance of CXCR4 on cerebellar development and motor behaviour by conditional...

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Detalhes bibliográficos
Main Authors: Huang, Guo-Jen, Edwards, Andrew, Tsai, Cheng-Yu, Lee, Yi-Shin, Peng, Lei, Era, Takumi, Hirabayashi, Yoshio, Tsai, Ching-Yen, Nishikawa, Shin-Ichi, Iwakura, Yoichiro, Chen, Shu-Jen, Flint, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917845/
https://ncbi.nlm.nih.gov/pubmed/24516532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086471
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