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l-Serine and glycine serve as major astroglia-derived trophic factors for cerebellar Purkinje neurons

Glial cells support the survival and development of central neurons through the supply of trophic factors. Here we demonstrate that l-serine (l-Ser) and glycine (Gly) also are glia-derived trophic factors. These amino acids are released by astroglial cells and promote the survival, dendritogenesis,...

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Detalhes bibliográficos
Main Authors: Furuya, Shigeki, Tabata, Toshihide, Mitoma, Junya, Yamada, Keiko, Yamasaki, Miwako, Makino, Asami, Yamamoto, Toshifumi, Watanabe, Masahiko, Kano, Masanobu, Hirabayashi, Yoshio
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC17234/
https://ncbi.nlm.nih.gov/pubmed/11016963
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