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Intrinsic GTPase activity distinguishes normal and oncogenic ras p21 molecules.

The 21-kilodalton protein (p21) encoded by normal cellular Harvey-ras has been expressed in Escherichia coli as a fusion protein by using the pUC8 vector and has been purified to greater than 95% homogeneity by ion-exchange chromatography and gel filtration. The purified protein molecules possess in...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gibbs, J B, Sigal, I S, Poe, M, Scolnick, E M
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1984
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC391779/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6148751/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.18.5704
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