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Aldehyde dehydrogenase variation enhances effect of pesticides associated with Parkinson disease

OBJECTIVE: The objective of this study was to determine whether environmental and genetic alterations of neuronal aldehyde dehydrogenase (ALDH) enzymes were associated with increased Parkinson disease (PD) risk in an epidemiologic study. METHODS: A novel ex vivo assay was developed to identify pesti...

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Hlavní autoři: Fitzmaurice, Arthur G., Rhodes, Shannon L., Cockburn, Myles, Ritz, Beate, Bronstein, Jeff M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917685/
https://ncbi.nlm.nih.gov/pubmed/24491970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000000083
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