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Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease

Parkinson disease (PD) is a neurodegenerative disorder particularly characterized by the loss of dopaminergic neurons in the substantia nigra. Pesticide exposure has been associated with PD occurrence, and we previously reported that the fungicide benomyl interferes with several cellular processes p...

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Detalhes bibliográficos
Main Authors: Fitzmaurice, Arthur G., Rhodes, Shannon L., Lulla, Aaron, Murphy, Niall P., Lam, Hoa A., O’Donnell, Kelley C., Barnhill, Lisa, Casida, John E., Cockburn, Myles, Sagasti, Alvaro, Stahl, Mark C., Maidment, Nigel T., Ritz, Beate, Bronstein, Jeff M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545765/
https://ncbi.nlm.nih.gov/pubmed/23267077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220399110
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