Aldehyde dehydrogenase inhibition as a pathogenic mechanism in Parkinson disease

Parkinson disease (PD) is a neurodegenerative disorder particularly characterized by the loss of dopaminergic neurons in the substantia nigra. Pesticide exposure has been associated with PD occurrence, and we previously reported that the fungicide benomyl interferes with several cellular processes p...

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Detalles Bibliográficos
Autores principales: Fitzmaurice, Arthur G., Rhodes, Shannon L., Lulla, Aaron, Murphy, Niall P., Lam, Hoa A., O’Donnell, Kelley C., Barnhill, Lisa, Casida, John E., Cockburn, Myles, Sagasti, Alvaro, Stahl, Mark C., Maidment, Nigel T., Ritz, Beate, Bronstein, Jeff M.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2013
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545765/
https://ncbi.nlm.nih.gov/pubmed/23267077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1220399110
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