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Aldehyde dehydrogenase variation enhances effect of pesticides associated with Parkinson disease

OBJECTIVE: The objective of this study was to determine whether environmental and genetic alterations of neuronal aldehyde dehydrogenase (ALDH) enzymes were associated with increased Parkinson disease (PD) risk in an epidemiologic study. METHODS: A novel ex vivo assay was developed to identify pesti...

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Autors principals: Fitzmaurice, Arthur G., Rhodes, Shannon L., Cockburn, Myles, Ritz, Beate, Bronstein, Jeff M.
Format: Artigo
Idioma:Inglês
Publicat: Lippincott Williams & Wilkins 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3917685/
https://ncbi.nlm.nih.gov/pubmed/24491970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000000083
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