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Mass Spectrometry for the Biophysical Characterization of Therapeutic Monoclonal Antibodies
Monoclonal antibodies (mAbs) are powerful therapeutics, and their characterization has drawn considerable attention and urgency. Unlike small-molecular drugs (150-600 Da) that have rigid structures, mAbs (~150 kDa) are engineered proteins that undergo complicated folding and can exist in a number of...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3917544/ https://ncbi.nlm.nih.gov/pubmed/24291257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2013.11.027 |
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