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TorsinA rescues ER-associated stress and locomotive defects in C. elegans models of ALS
Molecular mechanisms underlying neurodegenerative diseases converge at the interface of pathways impacting cellular stress, protein homeostasis and aging. Targeting the intrinsic capacities of neuroprotective proteins to restore neuronal function and/or attenuate degeneration represents a potential...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Limited
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3917244/ https://ncbi.nlm.nih.gov/pubmed/24311730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.013615 |
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