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The early-onset torsion dystonia-associated protein, torsinA, displays molecular chaperone activity in vitro

TorsinA is a member of the AAA+ ATPase family of proteins and, notably, is the only known ATPase localized to the ER lumen. It has been suggested to act as a molecular chaperone, while a mutant form associated with early-onset torsion dystonia, a dominantly inherited movement disorder, appears to re...

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Detalhes bibliográficos
Main Authors: Burdette, Alexander J., Churchill, Perry F., Caldwell, Guy A., Caldwell, Kim A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006618/
https://ncbi.nlm.nih.gov/pubmed/20169475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-010-0173-2
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