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Inhibition of DNA synthesis by an electrophilic metabolite of benzo[a]pyrene.

Mitogen-stimulated scheduled DNA synthesis and DNA excision repair in human lymphocytes, as well as DNA polymerase a activity in a cell-free system, were inhibited by an electrophilic metabolite of benzo[a]pyrene. This metabolite, (+/-)-anti-(7r,8t)-dihydroxy-(9,10t)-epoxy-7,8,9,10-tetrahyd robenzo[...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Busbee, D L, Joe, C O, Norman, J O, Rankin, P W
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1984
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC391691/
https://ncbi.nlm.nih.gov/pubmed/6089190
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