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Pre-Clinical Assessment of Immune Responses to Adeno-Associated Virus (AAV) Vectors
Transitioning to human trials from pre-clinical models resulted in the emergence of inhibitory AAV vector immune responses which has become a hurdle for sustained correction. Early animal studies did not predict the full range of host immunity to the AAV vector in human studies. While pre-existing a...
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| Główni autorzy: | , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Frontiers Media S.A.
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3916775/ https://ncbi.nlm.nih.gov/pubmed/24570676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2014.00028 |
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