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A Panel of CpG Methylation Sites Distinguishes Human Embryonic Stem Cells and Induced Pluripotent Stem Cells

Whether human induced pluripotent stem cells (hiPSCs) are epigenetically identical to human embryonic stem cells (hESCs) has been debated in the stem cell field. In this study, we analyzed DNA methylation patterns in a large number of hiPSCs (n = 114) and hESCs (n = 155), and identified a panel of 8...

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Detalhes bibliográficos
Main Authors: Huang, Kevin, Shen, Yin, Xue, Zhigang, Bibikova, Marina, April, Craig, Liu, Zhenshan, Cheng, Linzhao, Nagy, Andras, Pellegrini, Matteo, Fan, Jian-Bing, Fan, Guoping
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916755/
https://ncbi.nlm.nih.gov/pubmed/24511466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2013.11.003
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