Evidence for Hysteretic Substrate Channeling in the Proline Dehydrogenase and Δ(1)-Pyrroline-5-carboxylate Dehydrogenase Coupled Reaction of Proline Utilization A (PutA)

PutA (proline utilization A) is a large bifunctional flavoenzyme with proline dehydrogenase (PRODH) and Δ(1)-pyrroline-5-carboxylate dehydrogenase (P5CDH) domains that catalyze the oxidation of l-proline to l-glutamate in two successive reactions. In the PRODH active site, proline undergoes a two-el...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Moxley, Michael A., Sanyal, Nikhilesh, Krishnan, Navasona, Tanner, John J., Becker, Donald F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
Témata:
Enzymology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916563/
https://ncbi.nlm.nih.gov/pubmed/24352662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.523704
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky