The Fibrinogen-binding M1 Protein Reduces Pharyngeal Cell Adherence and Colonization Phenotypes of M1T1 Group A Streptococcus

Group A Streptococcus (GAS) is a leading human pathogen producing a diverse array of infections from simple pharyngitis (“strep throat”) to invasive conditions, including necrotizing fasciitis and toxic shock syndrome. The surface-anchored GAS M1 protein is a classical virulence factor that promotes...

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Hauptverfasser: Anderson, Ericka L., Cole, Jason N., Olson, Joshua, Ryba, Bryan, Ghosh, Partho, Nizet, Victor
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916555/
https://ncbi.nlm.nih.gov/pubmed/24356958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.529537
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