N-Acetylglucosaminylation of Serine-Aspartate Repeat Proteins Promotes Staphylococcus aureus Bloodstream Infection

Staphylococcus aureus secretes products that convert host fibrinogen to fibrin and promote its agglutination with fibrin fibrils, thereby shielding bacteria from immune defenses. The agglutination reaction involves ClfA (clumping factor A), a surface protein with serine-aspartate (SD) repeats that c...

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Bibliographic Details
Main Authors: Thomer, Lena, Becker, Samuel, Emolo, Carla, Quach, Austin, Kim, Hwan Keun, Rauch, Sabine, Anderson, Mark, LeBlanc, James F., Schneewind, Olaf, Faull, Kym F., Missiakas, Dominique
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2014
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916549/
https://ncbi.nlm.nih.gov/pubmed/24344128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.532655
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