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A monoclonal antibody that recognizes the E domain of staphylococcal protein A

Staphylococcal protein A (SpA) binds Fcγ and V(H)3 clan Fab domains of human and animal immunoglobulin (Ig) with each of its five Ig binding domains (IgBDs), thereby supporting Staphylococcus aureus escape from opsonophagocytic killing and suppressing adaptive B cell responses. The variant SpA(KKAA)...

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Détails bibliographiques
Publié dans:Vaccine
Auteurs principaux: Kim, Hwan Keun, Emolo, Carla, Missiakas, Dominique, Schneewind, Olaf
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6211298/
https://ncbi.nlm.nih.gov/pubmed/24291195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.11.054
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