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A monoclonal antibody that recognizes the E domain of staphylococcal protein A

Staphylococcal protein A (SpA) binds Fcγ and V(H)3 clan Fab domains of human and animal immunoglobulin (Ig) with each of its five Ig binding domains (IgBDs), thereby supporting Staphylococcus aureus escape from opsonophagocytic killing and suppressing adaptive B cell responses. The variant SpA(KKAA)...

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Bibliografiske detaljer
Udgivet i:Vaccine
Main Authors: Kim, Hwan Keun, Emolo, Carla, Missiakas, Dominique, Schneewind, Olaf
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6211298/
https://ncbi.nlm.nih.gov/pubmed/24291195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.11.054
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