Loading...

Protein A-neutralizing monoclonal antibody protects neonatal mice against Staphylococcus aureus

Staphylococcus aureus is a cause of sepsis and meningitis in very-low-birth-weight (VLBW) infants. Clinical trials with S. aureus specific antibodies failed to protect VLBW neonates, which may be due to the immune evasive attributes of staphylococcal protein A (SpA). Here we show that mouse monoclon...

Full description

Saved in:
Bibliographic Details
Published in:Vaccine
Main Authors: Thammavongsa, Vilasack, Rauch, Sabine, Kim, Hwan Keun, Missiakas, Dominique M., Schneewind, Olaf
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378561/
https://ncbi.nlm.nih.gov/pubmed/25488332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.11.051
Tags: Add Tag
No Tags, Be the first to tag this record!