Protein A-neutralizing monoclonal antibody protects neonatal mice against Staphylococcus aureus

Staphylococcus aureus is a cause of sepsis and meningitis in very-low-birth-weight (VLBW) infants. Clinical trials with S. aureus specific antibodies failed to protect VLBW neonates, which may be due to the immune evasive attributes of staphylococcal protein A (SpA). Here we show that mouse monoclon...

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Bibliografiske detaljer
Udgivet i:Vaccine
Main Authors: Thammavongsa, Vilasack, Rauch, Sabine, Kim, Hwan Keun, Missiakas, Dominique M., Schneewind, Olaf
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4378561/
https://ncbi.nlm.nih.gov/pubmed/25488332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.11.051
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