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Protein A Suppresses Immune Responses during Staphylococcus aureus Bloodstream Infection in Guinea Pigs

Staphylococcus aureus infection is not associated with the development of protective immunity, and disease relapses occur frequently. We hypothesize that protein A, a factor that binds immunoglobulin Fcγ and cross-links V(H)3 clan B cell receptors (IgM), is the staphylococcal determinant for host im...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Kim, Hwan Keun, Falugi, Fabiana, Thomer, Lena, Missiakas, Dominique M., Schneewind, Olaf
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313907/
https://ncbi.nlm.nih.gov/pubmed/25564466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02369-14
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