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Role of Protein A in the Evasion of Host Adaptive Immune Responses by Staphylococcus aureus

Heritable defects in human B cell/antibody development are not associated with increased susceptibility to Staphylococcus aureus infection. Protein A (SpA), a surface molecule of S. aureus, binds the Fcγ domain of immunoglobulin (Ig) and cross-links the Fab domain of V(H)3-type B cell receptors (IgM...

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Autori principali: Falugi, Fabiana, Kim, Hwan Keun, Missiakas, Dominique M., Schneewind, Olaf
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Microbiology 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760252/
https://ncbi.nlm.nih.gov/pubmed/23982075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00575-13
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