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A Gammaherpesvirus Bcl-2 Ortholog Blocks B Cell Receptor-Mediated Apoptosis and Promotes the Survival of Developing B Cells In Vivo

Gammaherpesviruses such as Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV, HHV-8) establish lifelong latency in their hosts and are associated with the development of several types of malignancies, including a subset of B cell lymphomas. These viruses are thought to...

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Autores principales: Coleman, Carrie B., McGraw, Jennifer E., Feldman, Emily R., Roth, Alexa N., Keyes, Lisa R., Grau, Katrina R., Cochran, Stephanie L., Waldschmidt, Thomas J., Liang, Chengyu, Forrest, J. Craig, Tibbetts, Scott A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916410/
https://ncbi.nlm.nih.gov/pubmed/24516386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003916
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