A Gammaherpesvirus Bcl-2 Ortholog Blocks B Cell Receptor-Mediated Apoptosis and Promotes the Survival of Developing B Cells In Vivo

Gammaherpesviruses such as Epstein-Barr virus (EBV) and Kaposi's sarcoma-associated herpesvirus (KSHV, HHV-8) establish lifelong latency in their hosts and are associated with the development of several types of malignancies, including a subset of B cell lymphomas. These viruses are thought to...

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Detalhes bibliográficos
Main Authors: Coleman, Carrie B., McGraw, Jennifer E., Feldman, Emily R., Roth, Alexa N., Keyes, Lisa R., Grau, Katrina R., Cochran, Stephanie L., Waldschmidt, Thomas J., Liang, Chengyu, Forrest, J. Craig, Tibbetts, Scott A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916410/
https://ncbi.nlm.nih.gov/pubmed/24516386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003916
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