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Use of a Virus-Encoded Enzymatic Marker Reveals that a Stable Fraction of Memory B Cells Expresses Latency-Associated Nuclear Antigen throughout Chronic Gammaherpesvirus Infection

An integral feature of gammaherpesvirus infections is the ability to establish lifelong latency in B cells. During latency, the viral genome is maintained as an extrachomosomal episome, with stable maintenance in dividing cells mediated by the viral proteins Epstein-Barr nuclear antigen 1 (EBNA-1) f...

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Bibliografiske detaljer
Main Authors: Nealy, Michael S., Coleman, Carrie B., Li, Haiyan, Tibbetts, Scott A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897616/
https://ncbi.nlm.nih.gov/pubmed/20484501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02572-09
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