Evaluation in Mice of a Conjugate Vaccine for Cholera Made from Vibrio cholerae O1 (Ogawa) O-Specific Polysaccharide

BACKGROUND: Protective immunity against cholera is serogroup specific. Serogroup specificity in Vibrio cholerae is determined by the O-specific polysaccharide (OSP) of lipopolysaccharide (LPS). Generally, polysaccharides are poorly immunogenic, especially in young children. METHODOLOGY: Here we repo...

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Detalhes bibliográficos
Main Authors: Alam, Mohammad Murshid, Bufano, Megan Kelly, Xu, Peng, Kalsy, Anuj, Yu, Y., Freeman, Y. Wu, Sultana, Tania, Rashu, Md. Rasheduzzaman, Desai, Ishaan, Eckhoff, Grace, Leung, Daniel T., Charles, Richelle C., LaRocque, Regina C., Harris, Jason B., Clements, John D., Calderwood, Stephen B., Qadri, Firdausi, Vann, W. F., Kováč, Pavol, Ryan, Edward T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916310/
https://ncbi.nlm.nih.gov/pubmed/24516685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002683
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