Evaluation in Mice of a Conjugate Vaccine for Cholera Made from Vibrio cholerae O1 (Ogawa) O-Specific Polysaccharide

BACKGROUND: Protective immunity against cholera is serogroup specific. Serogroup specificity in Vibrio cholerae is determined by the O-specific polysaccharide (OSP) of lipopolysaccharide (LPS). Generally, polysaccharides are poorly immunogenic, especially in young children. METHODOLOGY: Here we repo...

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Hlavní autoři: Alam, Mohammad Murshid, Bufano, Megan Kelly, Xu, Peng, Kalsy, Anuj, Yu, Y., Freeman, Y. Wu, Sultana, Tania, Rashu, Md. Rasheduzzaman, Desai, Ishaan, Eckhoff, Grace, Leung, Daniel T., Charles, Richelle C., LaRocque, Regina C., Harris, Jason B., Clements, John D., Calderwood, Stephen B., Qadri, Firdausi, Vann, W. F., Kováč, Pavol, Ryan, Edward T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916310/
https://ncbi.nlm.nih.gov/pubmed/24516685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0002683
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