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Mechanistically Distinct Mouse Models for CRX-Associated Retinopathy
Cone-rod homeobox (CRX) protein is a “paired-like” homeodomain transcription factor that is essential for regulating rod and cone photoreceptor transcription. Mutations in human CRX are associated with the dominant retinopathies Retinitis Pigmentosa (RP), Cone-Rod Dystrophy (CoRD) and Leber Congenit...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Public Library of Science
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3916252/ https://ncbi.nlm.nih.gov/pubmed/24516401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004111 |
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