Identification of new ALK and RET gene fusions from colorectal and lung cancer biopsies

Applying a next-generation sequencing assay targeting 145 cancer-relevant genes in 40 colorectal cancer and 24 non–small cell lung cancer formalin-fixed paraffin-embedded tissue specimens identified at least one clinically relevant genomic alteration in 59% of the samples and revealed two gene fusio...

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Main Authors: Lipson, Doron, Capelletti, Marzia, Yelensky, Roman, Otto, Geoff, Parker, Alex, Jarosz, Mirna, Curran, John A, Balasubramanian, Sohail, Bloom, Troy, Brennan, Kristina W, Donahue, Amy, Downing, Sean R, Frampton, Garrett M, Garcia, Lazaro, Juhn, Frank, Mitchell, Kathy C, White, Emily, White, Jared, Zwirko, Zac, Peretz, Tamar, Nechushtan, Hovav, Soussan-Gutman, Lior, Kim, Jhingook, Sasaki, Hidefumi, Kim, Hyeong Ryul, Park, Seung-il, Ercan, Dalia, Sheehan, Christine E, Ross, Jeffrey S, Cronin, Maureen T, Jänne, Pasi A, Stephens, Philip J
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916180/
https://ncbi.nlm.nih.gov/pubmed/22327622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2673
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