Induction of heparanase by HPV E6 oncogene in head and neck squamous cell carcinoma

High-risk human papillomavirus (HPV)-positive head and neck squamous cell carcinomas (HNSCCs) are highly invasive; however the identity of downstream effectors responsible for their aggressive phenotype remains underinvestigated. Here, we report that HPV-mediated up-regulation of heparanase enzyme c...

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Bibliografiske detaljer
Main Authors: Hirshoren, Nir, Bulvik, Raanan, Neuman, Tzahi, Rubinstein, Ariel M, Meirovitz, Amichay, Elkin, Michael
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2014
Fag:
Short Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3916129/
https://ncbi.nlm.nih.gov/pubmed/24286246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12179
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