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Evolution of intratumoral phenotypic heterogeneity: the role of trait inheritance
A tumour is a heterogeneous population of cells that competes for limited resources. In the clinic, we typically probe the tumour by biopsy, and then characterize it by the dominant genetic clone. But genotypes are only the first link in the chain of hierarchical events that leads to a specific cell...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Royal Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3915835/ https://ncbi.nlm.nih.gov/pubmed/24511380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsfs.2013.0016 |
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