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Drivers of dynamic intratumor heterogeneity and phenotypic plasticity

Cancer is a clonal disease, i.e., all tumor cells within a malignant lesion trace their lineage back to a precursor somatic cell that acquired oncogenic mutations during development and aging. And yet, those tumor cells tend to have genetic and nongenetic variations among themselves—which is denoted...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Biswas, Antara, De, Subhajyoti
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8163571/
https://ncbi.nlm.nih.gov/pubmed/33657326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00575.2020
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