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DNA sequence-dependent mechanics and protein-assisted bending in repressor-mediated loop formation

As the chief informational molecule of life, DNA is subject to extensive physical manipulations. The energy required to deform double-helical DNA depends on sequence, and this mechanical code of DNA influences gene regulation, such as through nucleosome positioning. Here we examine the sequence-depe...

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Detalhes bibliográficos
Main Authors: Boedicker, James Q., Garcia, Hernan G., Johnson, Stephanie, Phillips, Rob
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915735/
https://ncbi.nlm.nih.gov/pubmed/24231252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/1478-3975/10/6/066005
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