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Sequence dependence of DNA bending rigidity

For many aspects of DNA–protein interaction, it is vital to know how DNA bending rigidity (or persistence length, a) depends on its sequence. We addressed this problem using the method based on cyclization of short DNA fragments, which allows very accurate determination of a. Our approach was based...

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Autori principali: Geggier, Stephanie, Vologodskii, Alexander
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2932579/
https://ncbi.nlm.nih.gov/pubmed/20702767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004809107
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