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Calcium-dependent oligonucleotide antagonists specific for L-selectin.

The selectins are calcium-dependent C-type lectins that recognize complex anionic carbohydrate ligands, initiating many cell-cell interactions in the vascular system. Selectin blockade shows therapeutic promise in a variety of inflammatory and postischemic pathologies. However, the available oligosa...

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Bibliografische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: O'Connell, D, Koenig, A, Jennings, S, Hicke, B, Han, H L, Fitzwater, T, Chang, Y F, Varki, N, Parma, D, Varki, A
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1996
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39156/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8650187/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.12.5883
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