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Damaged mitochondria and overproduction of ROS in Fanconi anemia cells

Fanconi anemia (FA) is a heterogeneous disease associated with a bone marrow failure, cancer predisposition and hypersensitivity to DNA crosslinking agents. To date, 15 different genes have been shown to cause FA, all of which have some role in repair of defective DNA interstrand crosslinks. On a bi...

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Kaydedildi:
Detaylı Bibliyografya
Yazar: Lyakhovich, Alex
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915560/
https://ncbi.nlm.nih.gov/pubmed/25002988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rdis.24048
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