Alpha-factor-directed synthesis and secretion of mature foreign proteins in Saccharomyces cerevisiae.

Saccharomyces cerevisiae cells were transformed with plasmids containing hybrid genes in which the sequence encoding mature human epidermal growth factor was joined to sequences encoding the leader region (preprosegment) of the precursor of the yeast mating pheromone alpha-factor. These cells accura...

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Main Authors: Brake, A J, Merryweather, J P, Coit, D G, Heberlein, U A, Masiarz, F R, Mullenbach, G T, Urdea, M S, Valenzuela, P, Barr, P J
Format: Artigo
Sprog:Inglês
Udgivet: 1984
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC391546/
https://ncbi.nlm.nih.gov/pubmed/6087338
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