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Lysine 394 is a novel Rad6B-induced ubiquitination site on beta-catenin
The ubiquitin conjugating enzyme Rad6B is overexpressed in breast cancer and induces β-catenin transcriptional activation and stabilization via K63-linked polyubiquitination. Here we identify β-catenin and Rad6B interacting regions, identify potential Rad6B ubiquitination sites in β-catenin, and cha...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3915360/ https://ncbi.nlm.nih.gov/pubmed/22705350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2012.05.032 |
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