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The Treg-Specific Demethylated Region Stabilizes Foxp3 Expression Independently of NF-κB Signaling
Regulatory T cells (Tregs) obtain immunosuppressive capacity by the upregulation of forkhead box protein 3 (Foxp3), and persistent expression of this transcription factor is required to maintain their immune regulatory function and ensure immune homeostasis. Stable Foxp3 expression is achieved throu...
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| Asıl Yazarlar: | , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3914969/ https://ncbi.nlm.nih.gov/pubmed/24505473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088318 |
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