The Treg-Specific Demethylated Region Stabilizes Foxp3 Expression Independently of NF-κB Signaling

Regulatory T cells (Tregs) obtain immunosuppressive capacity by the upregulation of forkhead box protein 3 (Foxp3), and persistent expression of this transcription factor is required to maintain their immune regulatory function and ensure immune homeostasis. Stable Foxp3 expression is achieved throu...

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Bibliographic Details
Main Authors:	Schreiber, Lisa, Pietzsch, Beate, Floess, Stefan, Farah, Carla, Jänsch, Lothar, Schmitz, Ingo, Huehn, Jochen
Format:	Artigo
Language:	Inglês
Published:	Public Library of Science 2014
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3914969/ https://ncbi.nlm.nih.gov/pubmed/24505473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0088318
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The Treg-Specific Demethylated Region Stabilizes Foxp3 Expression Independently of NF-κB Signaling

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