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Evidence for Paternal Age-Related Alterations in Meiotic Chromosome Dynamics in the Mouse

Increasing age in a woman is a well-documented risk factor for meiotic errors, but the effect of paternal age is less clear. Although it is generally agreed that spermatogenesis declines with age, the mechanisms that account for this remain unclear. Because meiosis involves a complex and tightly reg...

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Detalhes bibliográficos
Main Authors: Vrooman, Lisa A., Nagaoka, So I., Hassold, Terry J., Hunt, Patricia A.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914612/
https://ncbi.nlm.nih.gov/pubmed/24318536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.158782
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