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Thiol-redox antioxidants protect against lung vascular endothelial cytoskeletal alterations caused by pulmonary fibrosis inducer, bleomycin: comparison between classical thiol-protectant, N-acetyl-l-cysteine, and novel thiol antioxidant, N,N′-bis-2-mercaptoethyl isophthalamide

Lung vascular alterations and pulmonary hypertension associated with oxidative stress have been reported to be involved in idiopathic lung fibrosis (ILF). Therefore, here, we hypothesize that the widely used lung fibrosis inducer, bleomycin, would cause cytoskeletal rearrangement through thiol-redox...

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Bibliografische gegevens
Hoofdauteurs: Patel, Rishi B., Kotha, Sainath R., Sauers, Lynn A., Malireddy, Smitha, Gurney, Travis O., Gupta, Niladri N., Elton, Terry S., Magalang, Ulysses J., Marsh, Clay B., Haley, Boyd E., Parinandi, Narasimham L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914546/
https://ncbi.nlm.nih.gov/pubmed/22409285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/15376516.2012.673089
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