Thiol-redox antioxidants protect against lung vascular endothelial cytoskeletal alterations caused by pulmonary fibrosis inducer, bleomycin: comparison between classical thiol-protectant, N-acetyl-l-cysteine, and novel thiol antioxidant, N,N′-bis-2-mercaptoethyl isophthalamide

Lung vascular alterations and pulmonary hypertension associated with oxidative stress have been reported to be involved in idiopathic lung fibrosis (ILF). Therefore, here, we hypothesize that the widely used lung fibrosis inducer, bleomycin, would cause cytoskeletal rearrangement through thiol-redox...

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Detalhes bibliográficos
Main Authors: Patel, Rishi B., Kotha, Sainath R., Sauers, Lynn A., Malireddy, Smitha, Gurney, Travis O., Gupta, Niladri N., Elton, Terry S., Magalang, Ulysses J., Marsh, Clay B., Haley, Boyd E., Parinandi, Narasimham L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914546/
https://ncbi.nlm.nih.gov/pubmed/22409285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/15376516.2012.673089
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