Therapeutic Efficacy of the N,N′ Bis-(2-Mercaptoethyl) Isophthalamide Chelator for Methylmercury Intoxication in Caenorhabditis elegans

Methylmercury (MeHg) is a global pollutant and potent neurotoxin. In humans, MeHg damages the central nervous system (CNS), causing irreversible neuronal shrinkage, and neuronal loss. Most chelators for clinical mercury detoxification are thiol-containing agents. N,N ‘bis-(2-mercaptoethyl) isophthal...

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Détails bibliographiques
Publié dans:Neurotox Res
Auteurs principaux: Ke, Tao, Bornhorst, Julia, Schwerdtle, Tanja, Santamaría, Abel, Soare, Félix Alexandre Antunes, Rocha, João B. T., Farina, Marcelo, Bowman, Aaron B., Aschner, Michael
Format: Artigo
Langue:Inglês
Publié: 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924665/
https://ncbi.nlm.nih.gov/pubmed/32236898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12640-020-00194-0
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