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Proteostasis and longevity: when does aging really begin?

Aging is a complex process regulated by multiple cellular pathways, including the proteostasis network. The proteostasis network consists of molecular chaperones, stress-response transcription factors, and protein degradation machines that sense and respond to proteotoxic stress and protein misfoldi...

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Библиографические подробности
Главные авторы: Labbadia, John, Morimoto, Richard I.
Формат: Artigo
Язык:Inglês
Опубликовано: Faculty of 1000 Ltd 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914504/
https://ncbi.nlm.nih.gov/pubmed/24592319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12703/P6-7
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