Sustained peripheral depletion of amyloid-β with a novel form of neprilysin does not affect central levels of amyloid-β

Alzheimer’s disease is characterized by the accumulation of amyloid deposits in the brain and the progressive loss of cognitive functions. Although the precise role of amyloid-β in disease progression remains somewhat controversial, many efforts to halt or reverse disease progression have focussed o...

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Autori principali: Henderson, Simon J., Andersson, Christin, Narwal, Rajesh, Janson, Juliette, Goldschmidt, Tom J., Appelkvist, Paulina, Bogstedt, Anna, Steffen, Ann-Charlott, Haupts, Ulrich, Tebbe, Jan, Freskgård, Per Ola, Jermutus, Lutz, Burrell, Matthew, Fowler, Susan B., Webster, Carl I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3914468/
https://ncbi.nlm.nih.gov/pubmed/24259408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awt308
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